Current Studies

HPV Protocols Protocol Title
AMC-058 A Companion Protocol To Evaluate Anogenital Human Papillomavirus (HPV) Infection And Anogenital Squamous Intraepithelial Lesions (ASIL) In Patients Participating In AMC Clinical Trials
AMC-072 Protective Effect of quadrivalent vaccine in young HIV-positive males who have sex with males
AMC-081 (African Study) Feasibility Study of Safety, Toxicity, and Compliance of Concomitant Chemoradiotherapy for HIV-Associated Locally-Advanced Cervical Cancer 
AMC-084 Screening HIV-Infected Women for Anal Cancer Precursors
AMC-088 A Randomized Phase III Study of Intra-anal Imiquimod 2.5% vs. Topical 5-Fluorouracil 5% vs. Observation for the Treatment of High-grade Squamous Anal Intraepithelial Lesions (HSIL) in HIV-infected Men and Women
AMC-A01 Anal Cancer/HSIL Outcomes Research (ANCHOR) Study
KS Protocols Protocol Title
A5263/AMC-066 A Randomized Comparison of Three Regimens of Chemotherapy with Compatible Antiretroviral Therapy for Treatment of Advanced AIDS-KS in Resource-Limited Settings
A5264/AMC-067 A Randomized Comparison of Antiretroviral Therapy Alone or with Delayed Chemotherapy versus Antiretroviral Therapy with Immediate Adjunctive Chemotherapy for Treatment of Limited Stage AIDS-KS in Resource-Limited Settings
A5278s/AMC-074 Pharmacology Substudies of A5263 and A5264
Lymphoma Protocols Protocol Title
AMC-075 A Sequential Phase I/Randomized Phase II Trial of Vorinostat and Risk-Adapted Chemotherapy with Rituximab in HIV-Related B-cell Non-Hodgkin’s Lymphoma
BMT CTN 0803/AMC-080 Allogeneic Hematopoietic Cell Transplant for Hematological Cancers and Myelodysplastic Syndromes in HIV-Infected Individuals
AMC-085 A Phase 1/2 Study Examining AVD and Brentuximab Vedotin in Patients with HIV and Advanced Stage Hodgkin's Lymphoma
9177/AMC-086 Phase II Study of Dose-Adjusted EPOCH+/- Rituximab in Adults with Untreated Burkitt Lymphoma, C-Myc Positive Diffuse Large B-Cell Lymphoma and Plasmablastic Lymphoma
AMC-091 Phase I and Pharmacokinetic Study of Ibrutinib in HIV-infected Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
NADC Protocols Protocol Title
AMC-078  A Phase 1 Study of Vorinostat in Combination with Paclitaxel and Carboplatin in Solid Tumors (with Focus on Upper Aerodigestive Cancers) in Persons with HIV Infection
AMC-087 Phase I Trial of Cabozantinib (XL184) for Advanced Solid Tumors in Persons with HIV Infection
AMC-090 Phase I/Pharmacokinetic Trial of Erlotinib for Advanced Non-small Cell Lung Cancer in Persons with HIV Infection
Lab and Survey Protocols Protocol Title
A5278s/AMC-074 Pharmacology Substudies of A5263 and A5264
AMC-083 Tissue Acquisition for Analysis of Prognostic Factors, Immunology, and Genetic Progression of HIV-1 Associated Malignancies
AMC-S006

Participation in AMC Clinical Trials (IMPACTS)