Current Studies

HPV Protocols Protocol Title
AMC-088 A Randomized Phase III Study of Intra-anal Imiquimod 2.5% vs. Topical 5-Fluorouracil 5% vs. Observation for the Treatment of High-grade Squamous Anal Intraepithelial Lesions (HSIL) in HIV-infected Men and Women
AMC-092 A multicenter observational and feasibility study of excision of superficially invasive squamous cell carcinoma (SISCCA) of the anal canal and perianus in HIV-infected persons
AMC-103 A Phase 2 Evaluation of VGX-3100, a Synthetic DNA Immunotherapy Targeting Human Papillomavirus 16 and 18 E6 and E7 Proteins, for Anal High-Grade Squamous Intraepithelial Lesions (HSIL) in HIV-Positive Individuals
AMC-A01 Anal Cancer/HSIL Outcomes Research (ANCHOR) Study
KS Protocols Protocol Title
AMC-096 A Phase II Study of sEphB4-HSA in Kaposi Sarcoma
AMC-098 A Pilot Study of Nelfinavir for the Treatment of Kaposi Sarcoma
AMC-S007 Longitudinal Quality of Life Study Among Participants with AIDS-Associated Kaposi Sarcoma at Bugando Medical Centre, in Mwanza, Tanzania
Lymphoma Protocols Protocol Title
AMC-068 Randomized, Phase II Trial of CHOP vs. Oral Chemotherapy with Concomitant Antiretroviral Therapy in Patients with HIV-Associated Lymphoma in Sub-Saharan Africa
AMC-085 A Phase 1/2 Study Examining AVD and Brentuximab Vedotin in Patients with HIV and Advanced Stage Hodgkin's Lymphoma
AMC-086 / 9177 Phase II Study of Dose-Adjusted EPOCH+/- Rituximab in Adults with Untreated Burkitt Lymphoma, C-Myc Positive Diffuse Large B-Cell Lymphoma and Plasmablastic Lymphoma
AMC-097 A Phase I Study of Stem Cell Gene Therapy for HIV Mediated by Lentivector Transduced, Pre-Selected CD34+ Cells
AMC-101 Phase I and Dose-Expansion Study of Ibrutinib and R-da-EPOCH for Front Line Treatment of AIDS-Related Lymphomas
AMC-S004 Clinical and Genomic Factors for Prognosis of Primary Effusion Lymphoma
NADC Protocols Protocol Title
AMC-087 Phase I Trial of Cabozantinib (XL184) for Advanced Solid Tumors in Persons with HIV Infection
AMC-095 A Phase I Study of Ipilimumab and Nivolumab in Advanced HIV-Associated Solid Tumors, with Expansion Cohorts in HIV-Associated Solid Tumors and a Cohort of HIV-Associated Classical Hodgkin Lymphoma
Lab and Survey Protocols Protocol Title
AMC-083 Tissue Acquisition for Analysis of Prognostic Factors, Immunology, and Genetic Progression of HIV-1 Associated Malignancies